| 19 Sep 25 | Predictions | |
 |
Cardiff MU-The New Saints | 2 |
 |
Betis-Real Sociedad | 1X |
 |
Rio Ave-Porto | 2 |
 |
Willem II-Jong Ajax | +2.5 |
|
Roda-RKC Waalwijk | +2.5 |
 |
Lecce-Cagliari | -2.5 |
 |
Arminia Bielefeld-Greuther Furth | +2.5 |
|
Stuttgart-St. Pauli 1910 | +2.5 |
 |
Olympique Lyonnais-Angers | 1 |
 |
Middlesbrough-West Bromwich A. | 1X |
 |
Gent-Dender EH | 1 |